5-Amino-1mq 10mg research peptide vial by FYH Peptides
COA Verified
Metabolic Research Cat№ FYH-012

5-Amino-1mq

10mg • Powder
$68.16 USD / vial

5-Amino-1-methylquinolinium — small-molecule selective inhibitor of nicotinamide N-methyltransferase (NNMT). Research-grade powder for in vitro enzyme assay.

Technical Data

Catalog №
FYH-012
CAS №
134296-13-2
Purity (HPLC)
99.93%
Mol. Weight
159.21 g/mol
Mass / Vial
10mg
Form
Powder
Tested Batch №
5A-265A10-003
Storage
−20 °C, lyophilized
Origin
Switzerland, GMP-grade synthesis
Sequence / Structure
N/A — small-molecule quinolinium

Certificate of Analysis

5-Amino-1mq 10mg HPLC Certificate of Analysis — batch 5A-265A10-003 Click image to open full-resolution COA →
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Published Research

Peer-reviewed literature indexed on NCBI PubMed referencing 5-Amino-1mq. Listed for laboratory reference only — FYH Peptides makes no claim regarding the conclusions of any cited author. Click PubMed or DOI to read the original publication. Updated 2026-05-20.

  1. 1.
    NNMT inhibition in cancer-associated fibroblasts restores antitumour immunity.
    Heide J, Bilecz AJ, Patnaik S, et al.
    Nature · 2025
    PubMed DOI 10.1038/s41586-025-09303-5 PMID: 40702186
  2. 2.
    ER stress-induced upregulation of NNMT contributes to alcohol-related fatty liver development.
    Song Q, Chen Y, Wang J, et al.
    Journal of hepatology · 2020
    PubMed DOI 10.1016/j.jhep.2020.04.038 PMID: 32389809
  3. 3.
    NAD(+) metabolism enzyme NNMT in cancer-associated fibroblasts drives tumor progression and resistance to immunotherapy by modulating macrophages in urothelial bladder cancer.
    Yang M, Wang B, Hou W, et al.
    Journal for immunotherapy of cancer · 2024
    PubMed DOI 10.1136/jitc-2024-009281 PMID: 39067875
  4. 4.
    Nicotinamide-N-methyltransferase inhibition improves cardiac function and structure in a heart failure with preserved ejection fraction mouse model.
    Li S, Rodrigues PG, Chakraborty AD, et al.
    Pharmacological research · 2025
    PubMed DOI 10.1016/j.phrs.2025.107820 PMID: 40484359
  5. 5.
    NNMT inhibition counteracts tubular senescence and fibrosis in early stages of chronic kidney disease.
    Chanvillard L, Lantermans HC, Wall C, et al.
    Cell reports · 2026
    PubMed DOI 10.1016/j.celrep.2025.116823 PMID: 41543936
  6. 6.
    Nicotinamide N-methyl transferase (NNMT): An emerging therapeutic target.
    Gao Y, Martin NI, van Haren MJ
    Drug discovery today · 2021
    PubMed DOI 10.1016/j.drudis.2021.05.011 PMID: 34029690
  7. 7.
    Nicotinamide N -methyltransferase promotes M2 macrophage polarization by IL6 and MDSC conversion by GM-CSF in gallbladder carcinoma.
    Li Y, Yang B, Miao H, et al.
    Hepatology (Baltimore, Md.) · 2023
    PubMed DOI 10.1097/HEP.0000000000000028 PMID: 36633260
  8. 8.
    Nicotinamide N-methyltransferase: At the crossroads between cellular metabolism and epigenetic regulation.
    Roberti A, Fernández AF, Fraga MF
    Molecular metabolism · 2021
    PubMed DOI 10.1016/j.molmet.2021.101165 PMID: 33453420
⚠️ For Research Use Only. This product is sold exclusively for in vitro laboratory research use by qualified researchers and laboratories. It is NOT intended for human consumption, medical use, or as a dietary supplement. The FDA has not evaluated this product for safety or efficacy.

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