MOTS-C 10mg research peptide vial by FYH Peptides
COA Verified
Metabolic Research Cat№ FYH-004

MOTS-C

10mg • Lyophilized
$68.16 USD / vial

16-amino-acid peptide encoded within the 12S rRNA region of the mitochondrial genome. Used in in vitro laboratory research on cellular metabolic signaling.

Technical Data

Catalog №
FYH-004
CAS №
1627580-64-6
Purity (HPLC)
99.92%
Mol. Weight
2174.5 g/mol
Mass / Vial
10mg
Form
Lyophilized
Tested Batch №
MC-26MC10-004
Storage
−20 °C, lyophilized
Origin
Switzerland, GMP-grade synthesis
Sequence / Structure
Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg

Certificate of Analysis

MOTS-C 10mg HPLC Certificate of Analysis — batch MC-26MC10-004 Click image to open full-resolution COA →
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Published Research

Peer-reviewed literature indexed on NCBI PubMed referencing MOTS-C. Listed for laboratory reference only — FYH Peptides makes no claim regarding the conclusions of any cited author. Click PubMed or DOI to read the original publication. Updated 2026-05-20.

  1. 1.
    The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance.
    Lee C, Zeng J, Drew BG, et al.
    Cell metabolism · 2015
    PubMed DOI 10.1016/j.cmet.2015.02.009 PMID: 25738459
  2. 2.
    Mitochondrial-Derived Peptide MOTS-c Suppresses Ovarian Cancer Progression by Attenuating USP7-Mediated LARS1 Deubiquitination.
    Yin Y, Li Y, Ma B, et al.
    Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    PubMed DOI 10.1002/advs.202405620 PMID: 39321430
  3. 3.
    The mitochondrial-derived peptide MOTS-c relieves hyperglycemia and insulin resistance in gestational diabetes mellitus.
    Yin Y, Pan Y, He J, et al.
    Pharmacological research · 2022
    PubMed DOI 10.1016/j.phrs.2021.105987 PMID: 34798268
  4. 4.
    The Mitochondrial-Derived Peptide MOTS-c Alleviates Radiation Pneumonitis via an Nrf2-Dependent Mechanism.
    Zhang Y, Huang J, Zhang Y, et al.
    Antioxidants (Basel, Switzerland) · 2024
    PubMed DOI 10.3390/antiox13050613 PMID: 38790718
  5. 5.
    The Mitochondrial-Encoded Peptide MOTS-c Translocates to the Nucleus to Regulate Nuclear Gene Expression in Response to Metabolic Stress.
    Kim KH, Son JM, Benayoun BA, et al.
    Cell metabolism · 2018
    PubMed DOI 10.1016/j.cmet.2018.06.008 PMID: 29983246
  6. 6.
    MOTS-c reduces myostatin and muscle atrophy signaling.
    Kumagai H, Coelho AR, Wan J, et al.
    American journal of physiology. Endocrinology and metabolism · 2021
    PubMed DOI 10.1152/ajpendo.00275.2020 PMID: 33554779
  7. 7.
    Mitochondrial-derived microprotein MOTS-c attenuates immobilization-induced skeletal muscle atrophy by suppressing lipid infiltration.
    Kumagai H, Kim SJ, Miller B, et al.
    American journal of physiology. Endocrinology and metabolism · 2024
    PubMed DOI 10.1152/ajpendo.00285.2023 PMID: 38170165
  8. 8.
    MOTS-c: A promising mitochondrial-derived peptide for therapeutic exploitation.
    Zheng Y, Wei Z, Wang T
    Frontiers in endocrinology · 2023
    PubMed DOI 10.3389/fendo.2023.1120533 PMID: 36761202
⚠️ For Research Use Only. This product is sold exclusively for in vitro laboratory research use by qualified researchers and laboratories. It is NOT intended for human consumption, medical use, or as a dietary supplement. The FDA has not evaluated this product for safety or efficacy.

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